Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12055300 | 0.89 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHSD17B10KMT2AGAA | |
| SCHEMBL322669 | 0.83 | — | — | |
| SCHEMBL17263569 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10249500 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10412614 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL7602566 | 0.78 | TSHR (0.50) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL4482989 | 0.78 | GAA (0.52) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL807505 | 0.78 | — | — | |
| SCHEMBL18736731 | 0.78 | GAA (0.52) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| Acetic Acid SCHEMBL28767597 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| US-9427501-B2 | Coatings with crystallized active agent(s) and methods | SURMODICS, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8241921-B2 | Active agent eluting matrices with particulates | SURMODICS, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20100303878-A1 | BIODEGRADABLE BIOACTIVE AGENT RELEASING MATRICES WITH PARTICULATES | SURMODICS MD, LLC | 2010-12-02 | — | — | US | disclosed |
| US-20100166829-A1 | ACTIVE AGENT ELUTING MATRICES WITH PARTICULATES | SURMODICS, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-7709049-B2 | Methods, devices, and coatings for controlled active agent release | SURMODICS, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-7253277-B2 | Nanoparticle polyanion conjugates and methods of use thereof in detecting analytes | NANOSPHERE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20070101933-A1 | Method and Apparatus for Coating of Substrates | SURMODICS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| US-20070054127-A1 | SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS | Surmodics Coatings, LLC | 2007-03-08 | — | — | US | disclosed |
| US-7186814-B2 | Bioconjugate-nanoparticle probes | NANOSPHERE, INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070026037-A1 | Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility | Surmodics Coatings, LLC | 2007-02-01 | — | — | US | disclosed |
| EP-0191507-B1 | NEW 2-OXYIMINO-3-OXOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |
| EP-0057422-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-12 | — | — | EP | disclosed |
| EP-0191507-A2 | New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4452851-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0057422-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166829-A1 | ACTIVE AGENT ELUTING MATRICES WITH PARTICULATES | MIF, CD47, CD68 | ALDH1A1 1206/4885LMNA 866/4885HSD17B10 4185/4885 |
| US-20070026037-A1 | Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility | CD47, GP6, MSN | ALDH1A1 2441/4885LMNA 2808/4885HSD17B10 4318/4885 |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | REN, AGTR1, AGTR2 | ALDH1A1 484/4885LMNA 1723/4885HSD17B10 976/4885 |
| US-20100303878-A1 | BIODEGRADABLE BIOACTIVE AGENT RELEASING MATRICES WITH PARTICULATES | BMP2, MIF, BMP1 | ALDH1A1 3124/4885LMNA 2471/4885HSD17B10 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.