Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | LONP1 | P36776 | 1/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360065 | 0.84 | MMP1 (0.51) | MMP8MMP9MMP2MMP1MMP3 | |
| SCHEMBL6420230 | 0.83 | LMNA (0.41) | MMP8MMP9PSMB11PSMA7PSMB1 | |
| SCHEMBL7364715 | 0.82 | L3MBTL1 (0.45) | MMP8L3MBTL1MMP1 | |
| SCHEMBL7357404 | 0.82 | CHRNB2 (0.48) | L3MBTL1 | |
| SCHEMBL7357715 | 0.81 | NPC1 (0.49) | MMP8MMP9PSMB11PSMA7PSMB1 | |
| SCHEMBL7354243 | 0.81 | NAALAD2 (0.52) | MMP9L3MBTL1MMP2 | |
| SCHEMBL8749847 | 0.81 | NAALAD2 (0.52) | MMP9L3MBTL1MMP2 | |
| SCHEMBL7363512 | 0.80 | MMP3 (0.45) | MMP8KMT2APSMB11PSMA7PSMB1 | |
| SCHEMBL7357691 | 0.79 | CTSL (0.45) | MMP8PSMB1PSMB5PSMB2MMP2 | |
| SCHEMBL7357664 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340709-B1 | ADMINISTERING BIPHENYLSULFONAMIDE DERIVATIVE | WARNER-LAMBERT COMPANY | 2002-01-22 | — | — | US | disclosed |