Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 9/20 | 0.51 |
| ▸ | ACE | P12821 | 8/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354243 | 1.00 | NAALAD2 (0.52) | NAALAD2MMEACECPA1ACE2 | |
| SCHEMBL7360065 | 0.90 | MMP1 (0.51) | MMP2MMP7MMP9 | |
| SCHEMBL7357715 | 0.89 | NPC1 (0.49) | LMNAMMP9 | |
| SCHEMBL7363512 | 0.88 | MMP3 (0.45) | MMP2 | |
| SCHEMBL7357691 | 0.87 | CTSL (0.45) | MMEACEMMP2 | |
| SCHEMBL7364715 | 0.86 | L3MBTL1 (0.45) | NAALAD2MMEACEL3MBTL1 | |
| SCHEMBL7357664 | 0.86 | ALDH1A1 (0.54) | — | |
| SCHEMBL7357404 | 0.85 | CHRNB2 (0.48) | L3MBTL1 | |
| SCHEMBL7358630 | 0.84 | CTSL (0.43) | MMP2 | |
| SCHEMBL7365041 | 0.82 | MMP9 (0.55) | NAALAD2MMEACEMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691382-A | ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| EP-0667770-B1 | INHIBITION OF TNF PRODUCTION | BRITISH BIOTECH PHARM (GB) | 1997-03-19 | — | — | EP | disclosed |