SCHEMBL7632267

SCHEMBL7632267

CC(OC(=O)[C@@H]1CCC(=O)N1)C(=O)OCC(O)CO

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
CNR1 P21554 1/20 0.40
DAGLA Q9Y4D2 1/20 0.40
GAA P10253 1/20 0.39
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.34
HCRTR2 O43614 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1627195 0.85 GAA (0.47) LMNACNR1DAGLAGAATSHR
SCHEMBL1627193 0.85 GAA (0.47) LMNACNR1DAGLAGAATSHR
SCHEMBL10632344 0.83 LMNA (0.38) LMNACNR1DAGLAGAATSHR
SCHEMBL7635759 0.83 LMNA (0.47) LMNACNR1DAGLAGAATSHR
SCHEMBL8761598 0.81 CNR1 (0.44) LMNACNR1DAGLAGAATSHR
SCHEMBL7643521 0.80 CNR1 (0.52) LMNACNR1DAGLAGAAMEN1
SCHEMBL8749217 0.80 LMNA (0.43) LMNACNR1DAGLAGAATSHR
SCHEMBL8749152 0.77 LMNA (0.42) LMNACNR1DAGLAGAATSHR
SCHEMBL8749155 0.77 LMNA (0.42) LMNACNR1DAGLAGAATSHR
SCHEMBL8749016 0.77 CNR1 (0.51) LMNACNR1DAGLAGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
US-4774255-A SKIN DISORDERS LEVER BROTHERS COMPANY (US) 1988-09-27 US claimed
US-20130042482-A1 Skin Engaging Member Comprising An Anti-Irritation Agent THE GILLETTE COMPANY LLC 2013-02-21 US disclosed
US-20020119174-A1 Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates PROCTER & GAMBLE COMPANY, THE 2002-08-29 US disclosed
US-20020035070-A1 Method of regulating hair growth using metal complexes of oxidized carbohydrates THE PROCTER & GAMBLE COMPANY 2002-03-21 US disclosed
WO-2002007685-A2 METHOD OF REGULATING HAIR GROWTH USING METAL COMPLEXES OF OXIDIZED CARBOHYDRATES THE PROCTER & GAMBLE COMPANY (US) 2002-01-31 WO disclosed
WO-2002007700-A2 COMPOSITIONS USEFUL FOR REGULATING HAIR GROWTH CONTAINING METAL COMPLEXES OF OXIDIZED CARBOHYDRATES THE PROCTER & GAMBLE COMPANY (US) 2002-01-31 WO disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0375388-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-02 EP disclosed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP disclosed
EP-0398669-B1 Cosmetic composition UNILEVER PLC (GB) 1994-01-05 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP disclosed
EP-0531111-A1 Cosmetic composition UNILEVER PLC (GB) 1993-03-10 EP disclosed
EP-0348184-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1993-03-03 EP disclosed
EP-0335554-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1992-07-08 EP disclosed
EP-0490581-A1 Cosmetic composition UNILEVER PLC (GB) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119174-A1 Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates OSTC, LPO, UGCG LMNA 3933/4885CNR1 3357/4885DAGLA 1160/4885
US-20130042482-A1 Skin Engaging Member Comprising An Anti-Irritation Agent CUTA, ITCH, DSG1 LMNA 3331/4885CNR1 2269/4885DAGLA 90/4885
US-20020035070-A1 Method of regulating hair growth using metal complexes of oxidized carbohydrates OSTC, SOD1, OTC LMNA 4710/4885CNR1 3805/4885DAGLA 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.