Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761598 | 0.89 | CNR1 (0.44) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8749217 | 0.85 | LMNA (0.43) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8762023 | 0.85 | LMNA (0.44) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8748849 | 0.85 | LMNA (0.44) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8748821 | 0.84 | LMNA (0.46) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8761471 | 0.84 | LMNA (0.46) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8749016 | 0.84 | CNR1 (0.51) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL8762005 | 0.84 | CNR1 (0.51) | LMNACNR1DAGLAGAATSHR | |
| Isopropyl Alcohol SCHEMBL28077462 | 0.84 | LMNA (0.53) | LMNACNR1DAGLAGAATSHR | |
| SCHEMBL815103 | 0.83 | LMNA (0.58) | LMNACNR1DAGLAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0277428-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-03-23 | — | — | EP | claimed |
| EP-0342054-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1993-11-03 | — | — | EP | claimed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342055-A2 | Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0342054-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0176217-B1 | PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS | UNILEVER PLC (GB) | 1989-06-07 | — | — | EP | claimed |
| US-4774255-A | SKIN DISORDERS | LEVER BROTHERS COMPANY (US) | 1988-09-27 | — | — | US | claimed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | claimed |
| EP-2744473-A1 | SKIN ENGAGING MEMBER COMPRISING AN ANTI-IRRITATION AGENT | The Gillette Company (US) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013025857-A1 | SKIN ENGAGING MEMBER COMPRISING AN ANTI-IRRITATION AGENT | THE GILLETTE COMPANY (US) | 2013-02-21 | — | — | WO | disclosed |
| US-20130042482-A1 | Skin Engaging Member Comprising An Anti-Irritation Agent | THE GILLETTE COMPANY LLC | 2013-02-21 | — | — | US | disclosed |
| US-20020119174-A1 | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates | PROCTER & GAMBLE COMPANY, THE | 2002-08-29 | — | — | US | disclosed |
| US-20020035070-A1 | Method of regulating hair growth using metal complexes of oxidized carbohydrates | THE PROCTER & GAMBLE COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-0334586-A1 | Carbohydrate lactam derivatives and their use in cosmetic compositions | UNILEVER PLC (GB) | 1989-09-27 | — | — | EP | disclosed |
| EP-0334585-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-09-27 | — | — | EP | disclosed |
| EP-0176217-B1 | PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS | UNILEVER PLC (GB) | 1989-06-07 | — | — | EP | disclosed |
| US-4832946-A | CELL CULTURE FOR HAIR GROWTH | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY | 1989-05-23 | — | — | US | disclosed |
| EP-0277428-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0272920-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1988-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119174-A1 | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates | OSTC, LPO, UGCG | LMNA 3933/4885CNR1 3357/4885DAGLA 1160/4885 |
| US-20130042482-A1 | Skin Engaging Member Comprising An Anti-Irritation Agent | CUTA, ITCH, DSG1 | LMNA 3331/4885CNR1 2269/4885DAGLA 90/4885 |
| US-20020035070-A1 | Method of regulating hair growth using metal complexes of oxidized carbohydrates | OSTC, SOD1, OTC | LMNA 4710/4885CNR1 3805/4885DAGLA 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.