Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.56 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.56 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780302 | 0.76 | CA1 (0.64) | CA1CA2CA12CA7CA14 | |
| Hydrogen Sulfide SCHEMBL27905249 | 0.75 | CA1 (0.56) | CA1CA2CA12CA7CA14 | |
| Ammonia Solution, Strong SCHEMBL28150613 | 0.74 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL777246 | 0.73 | CA1 (0.59) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11575485 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 | |
| SCHEMBL5177545 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 | |
| SCHEMBL9589016 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 | |
| SCHEMBL14779905 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11575489 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 | |
| SCHEMBL17088827 | 0.72 | CA1 (0.58) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| CN-218686455-U | Be applied to rectifier unit in sodium cyclamate preparation process | 苏州纽特食品科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-113956186-A | Preparation method of sodium cyclamate | 苏州纽特食品科技有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-105188642-B | Oral care compositions | 高露洁-棕榄公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-107982076-A | Oral care composition | 高露洁-棕榄公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-105188642-A | Oral care compositions | COLGATE PALMOLIVE CO | 2015-12-23 | — | — | CN | disclosed |
| US-6350795-B1 | ACOUSTIC PHASE-CHANGE CONDUCTIVE INK CONTAINING LOW MOLECULAR WEIGHT OXYALKYLENE SEGMENTS COMPLEXED WITH UREA DERIVATIVES | XEROX CORPORATION | 2002-02-26 | — | — | US | disclosed |
| US-6096125-A | Ink compositions | XEROX CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |