Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 7/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | MMP12 | P39900 | 4/20 | 0.34 |
| ▸ | MMP14 | P50281 | 4/20 | 0.34 |
| ▸ | MMP15 | P51511 | 4/20 | 0.34 |
| ▸ | MMP16 | P51512 | 4/20 | 0.34 |
| ▸ | MMP26 | Q9NRE1 | 4/20 | 0.34 |
| ▸ | MMP7 | P09237 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654948 | 0.92 | MMP1 (0.38) | KDM4EUSP2POLBHPGDALOX15 | |
| SCHEMBL7658355 | 0.90 | ESR1 (0.39) | KDM4EUSP2POLBHPGDALOX15 | |
| SCHEMBL7661855 | 0.90 | ESR1 (0.39) | KDM4EUSP2POLBHPGDALOX15 | |
| SCHEMBL7654117 | 0.86 | LMNA (0.35) | TSHRALDH1A1LMNAMMP1MMP2 | |
| Hydrochloric Acid SCHEMBL7654884 | 0.85 | ADH5 (0.42) | ALOX15TSHRCYP3A4ADH5ESR1 | |
| SCHEMBL7659207 | 0.83 | CHRNA7 (0.36) | ALDH1A1LMNACYP3A4MMP1MMP2 | |
| SCHEMBL7659859 | 0.81 | LMNA (0.39) | TSHRALDH1A1LMNAMMP1MMP2 | |
| SCHEMBL7649774 | 0.81 | GPR119 (0.39) | KDM4EUSP2POLBHPGDALOX15 | |
| SCHEMBL7656362 | 0.81 | PSEN1 (0.41) | KDM4EUSP2POLBHPGDALOX15 | |
| SCHEMBL7658123 | 0.80 | LMNA (0.42) | TSHRALDH1A1LMNAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |