Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | ADH5 | P11766 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | MMP14 | P50281 | 3/20 | 0.33 |
| ▸ | MMP15 | P51511 | 3/20 | 0.33 |
| ▸ | MMP16 | P51512 | 3/20 | 0.33 |
| ▸ | MMP26 | Q9NRE1 | 3/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7654884 | 0.91 | ADH5 (0.42) | CHRNA7HTR2AHTR2CHTR2BMLLT1 | |
| SCHEMBL7654948 | 0.90 | MMP1 (0.38) | CHRNA7HTR2AHTR2CHTR2BMMP8 | |
| SCHEMBL7652350 | 0.89 | MMP8 (0.36) | MMP8MMP3MMP1MMP2MMP9 | |
| SCHEMBL7661855 | 0.87 | ESR1 (0.39) | ADH5ESR1CYP19A1ESR2MMP1 | |
| SCHEMBL7658355 | 0.87 | ESR1 (0.39) | ADH5ESR1CYP19A1ESR2MMP1 | |
| SCHEMBL7651679 | 0.83 | KDM4E (0.44) | ADH5ESR1CYP19A1ESR2MMP1 | |
| SCHEMBL7654117 | 0.79 | LMNA (0.35) | MMP8MMP3MMP1MMP2MMP9 | |
| SCHEMBL7656362 | 0.78 | PSEN1 (0.41) | MMP8MMP3ESR1CYP19A1MMP1 | |
| SCHEMBL7649774 | 0.78 | GPR119 (0.39) | CHRNA7MMP8MMP3ESR1CYP19A1 | |
| SCHEMBL7659859 | 0.78 | LMNA (0.39) | MMP8MMP3MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |