Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649774 | 0.89 | GPR119 (0.39) | ALDH1A1KDM4EMAPTMMP1USP2 | |
| SCHEMBL7654948 | 0.88 | MMP1 (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7658355 | 0.86 | ESR1 (0.39) | CYP2D6ALDH1A1KDM4ESMN1; SMN2MMP1 | |
| SCHEMBL7661855 | 0.86 | ESR1 (0.39) | CYP2D6ALDH1A1KDM4ESMN1; SMN2MMP1 | |
| SCHEMBL7651679 | 0.81 | KDM4E (0.44) | CYP2D6ALDH1A1KDM4EMMP1USP2 | |
| Hydrochloric Acid SCHEMBL7654884 | 0.80 | ADH5 (0.42) | KMT2AMEN1TSHRALOX15CYP19A1 | |
| SCHEMBL7659207 | 0.78 | CHRNA7 (0.36) | ALDH1A1SMN1; SMN2MMP1LMNAMMP14 | |
| SCHEMBL7654117 | 0.78 | LMNA (0.35) | ALDH1A1SMN1; SMN2MMP1TSHRLMNA | |
| SCHEMBL7659859 | 0.78 | LMNA (0.39) | ALDH1A1KMT2ASMN1; SMN2MMP1TSHR | |
| SCHEMBL7658123 | 0.77 | LMNA (0.42) | ALDH1A1KMT2ASMN1; SMN2MMP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |