Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649098 | 0.85 | GPR119 (0.54) | DGAT1MAPTTP53POLBLMNA | |
| SCHEMBL7074013 | 0.79 | HDAC4 (0.56) | DGAT1PLK1MAPTPOLBLMNA | |
| SCHEMBL7649437 | 0.78 | PKM (0.46) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL7071693 | 0.76 | LMNA (0.55) | DGAT1PLK1MAPTPOLBLMNA | |
| SCHEMBL7074329 | 0.73 | MAPT (0.59) | DGAT1PLK1MAPTPOLBLMNA | |
| SCHEMBL7655612 | 0.69 | MAOA (0.42) | DGAT1PLK1MAPTLMNAHPGD | |
| SCHEMBL7069987 | 0.67 | MAOA (0.52) | DGAT1PLK1MAPTTP53MAOA | |
| SCHEMBL7076934 | 0.67 | L3MBTL1 (0.54) | LMNA | |
| SCHEMBL7070577 | 0.67 | SMN1; SMN2 (0.52) | MAPTPOLBLMNAHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4419949 | 0.66 | MAOA (0.51) | DGAT1PLK1MAPTTP53MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |