Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7652266 | 0.88 | MAPK14 (0.42) | CNR1 | |
| Dimethylamine SCHEMBL7649217 | 0.83 | ALDH1A1 (0.45) | L3MBTL1HTTLMNAGABRA2GABRB2 | |
| SCHEMBL7652925 | 0.82 | KDM4E (0.41) | HTTLMNAALOX12NPSR1OPRM1 | |
| Dimethylamine SCHEMBL7658435 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1 | |
| Dimethylamine SCHEMBL7656109 | 0.80 | OPRM1 (0.38) | LMNAOPRM1ADORA3KDM4EALDH1A1 | |
| SCHEMBL7649148 | 0.80 | HTT (0.47) | L3MBTL1HTTLMNAALOX12NPSR1 | |
| Dimethylamine SCHEMBL7653735 | 0.78 | ALDH1A1 (0.44) | NPSR1ALDH1A1 | |
| Dimethylamine SCHEMBL7656702 | 0.76 | ADORA3 (0.48) | L3MBTL1LMNAADORA3KDM4EALDH1A1 | |
| Dimethylamine SCHEMBL7652927 | 0.75 | MAPK14 (0.50) | L3MBTL1LMNAADORA3ALDH1A1CYP1A2 | |
| Dimethylamine SCHEMBL7655386 | 0.74 | ADORA2B (0.43) | HTTLMNANR1H3ADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |