Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7652932 | 0.88 | L3MBTL1 (0.42) | CNR1 | |
| Dimethylamine SCHEMBL7658435 | 0.87 | ALDH1A1 (0.44) | POLBPDE4BPDE4APDE4CPDE4D | |
| Dimethylamine SCHEMBL7656109 | 0.87 | OPRM1 (0.38) | MAPK14DHODH | |
| Dimethylamine SCHEMBL7653735 | 0.85 | ALDH1A1 (0.44) | DHODH | |
| Dimethylamine SCHEMBL7656702 | 0.82 | ADORA3 (0.48) | MEN1KMT2ADHODH | |
| Dimethylamine SCHEMBL7649217 | 0.80 | ALDH1A1 (0.45) | POLBMEN1KMT2A | |
| SCHEMBL7652262 | 0.80 | NOX4 (0.45) | MAPK14POLBPDE4BMEN1KMT2A | |
| SCHEMBL7652394 | 0.78 | HSD11B1 (0.45) | MAPK14POLBPDE4BCNR1MAPK11 | |
| Dimethylamine SCHEMBL7655386 | 0.78 | ADORA2B (0.43) | MAPK14PDE4BPDE4APDE4CPDE4D | |
| Dimethylamine SCHEMBL7652927 | 0.76 | MAPK14 (0.50) | MAPK14MEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |