Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL7653735

CCn1c(-c2ccccc2)nn(-c2ccccc2F)c1=O.CNC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ NPSR1 Q6W5P4 2/20 0.44
▸ GNRHR P30968 1/20 0.43
▸ DHODH Q02127 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL7658435 0.87 ALDH1A1 (0.44) ALDH1A1DHODH
Dimethylamine SCHEMBL7656109 0.87 OPRM1 (0.38) ALDH1A1DHODHHPGD
Dimethylamine SCHEMBL7652266 0.85 MAPK14 (0.42) DHODH
Dimethylamine SCHEMBL7656702 0.82 ADORA3 (0.48) ALDH1A1DHODH
SCHEMBL7653733 0.80 NPC1 (0.40) ALDH1A1NPSR1GNRHRNPC1RAB9A
Dimethylamine SCHEMBL7652490 0.79 DHODH (0.52) DHODH
Dimethylamine SCHEMBL7652932 0.78 L3MBTL1 (0.42) ALDH1A1NPSR1
SCHEMBL7658070 0.78 NPC1 (0.44) ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2
Dimethylamine SCHEMBL7655386 0.78 ADORA2B (0.43) ALDH1A1NPC1RAB9AHPGD
Dimethylamine SCHEMBL7652927 0.76 MAPK14 (0.50) ALDH1A1DHODHNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6492407-B2 NEUROPROTECTIVE ACTIVITY BOEHRINGER IMGELHEIM PHARMA KG (DE) 2002-12-10 — — US disclosed