Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 7/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660359 | 0.85 | MGLL (0.44) | LMNAMAPTOPRM1HPGDADORA2A | |
| Dimethylamine SCHEMBL7656223 | 0.82 | MGLL (0.41) | LMNAMAPTOPRM1HPGDADORA2A | |
| SCHEMBL7656105 | 0.80 | DRD2 (0.39) | HTR7HTR6HTR1ADRD2DRD3 | |
| SCHEMBL7655906 | 0.79 | POLB (0.41) | TAAR1HTR7HTR6HTR1ADRD2 | |
| SCHEMBL7659194 | 0.77 | ALDH1A1 (0.51) | MAPTOPRM1POLBHPGDADORA2A | |
| SCHEMBL7658070 | 0.74 | NPC1 (0.44) | — | |
| SCHEMBL7652394 | 0.74 | HSD11B1 (0.45) | OPRM1POLBHPGDADORA2AADORA2B | |
| SCHEMBL7652883 | 0.74 | OPRM1 (0.41) | HTR1AOPRM1HPGDADORA2AADORA2B | |
| SCHEMBL7652938 | 0.73 | ALDH1A1 (0.43) | HTR7HTR6HTR1ADRD2DRD3 | |
| SCHEMBL7656052 | 0.72 | ADORA1 (0.54) | MAPTADRA1AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |