Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655309 | 0.85 | CA1 (0.45) | ALDH1A1TSHRKDM4EHSD17B10KMT2A | |
| SCHEMBL7660359 | 0.84 | MGLL (0.44) | ALDH1A1TSHRMGLLADORA2BADORA2A | |
| SCHEMBL7652394 | 0.84 | HSD11B1 (0.45) | MGLLADORA2BADORA2APOLBOPRM1 | |
| SCHEMBL7658070 | 0.84 | NPC1 (0.44) | ALDH1A1MGLL | |
| SCHEMBL7652883 | 0.84 | OPRM1 (0.41) | ALDH1A1TSHRMGLLADORA2BADORA2A | |
| SCHEMBL7656052 | 0.82 | ADORA1 (0.54) | ALDH1A1TSHRMGLLKDM4EADORA2A | |
| SCHEMBL7652545 | 0.81 | ADORA3 (0.49) | ALDH1A1ADORA2BADORA2AKMT2AMAPT | |
| SCHEMBL9051830 | 0.81 | KMT2A (0.43) | ALDH1A1TSHRMGLLKDM4EALOX15 | |
| Dimethylamine SCHEMBL7656223 | 0.81 | MGLL (0.41) | ALDH1A1TSHRMGLLADORA2BADORA2A | |
| SCHEMBL7652938 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |