Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660359 | 0.96 | MGLL (0.44) | MGLLOPRM1ADORA2AADORA2BTSHR | |
| Dimethylamine SCHEMBL7656109 | 0.85 | OPRM1 (0.38) | MGLLOPRM1ADORA2AADORA2BTSHR | |
| SCHEMBL7656220 | 0.82 | TAAR1 (0.40) | OPRM1ADORA2AADORA2BHPGDLMNA | |
| SCHEMBL7659194 | 0.81 | ALDH1A1 (0.51) | MGLLOPRM1ADORA2AADORA2BTSHR | |
| SCHEMBL7652883 | 0.78 | OPRM1 (0.41) | MGLLOPRM1ADORA2AADORA2BTSHR | |
| SCHEMBL7658070 | 0.78 | NPC1 (0.44) | MGLLALDH1A1 | |
| SCHEMBL7652394 | 0.78 | HSD11B1 (0.45) | MGLLOPRM1ADORA2AADORA2BHPGD | |
| Dimethylamine SCHEMBL7655912 | 0.78 | HIF1A (0.43) | ADORA2ATSHRLMNAALDH1A1MEN1 | |
| SCHEMBL7656105 | 0.76 | DRD2 (0.39) | OPRM1ADORA2AADORA2BTSHRHPGD | |
| SCHEMBL7656052 | 0.76 | ADORA1 (0.54) | MGLLADORA2ATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |