Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662193 | 0.91 | ABL1 (0.44) | ABL1MAOBCA12CA9TP53 | |
| SCHEMBL7656276 | 0.86 | P2RY14 (0.46) | — | |
| SCHEMBL7656725 | 0.86 | NR4A2 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7652092 | 0.82 | ALDH1A1 (0.50) | TP53ALDH1A1MAPK1 | |
| SCHEMBL7659425 | 0.76 | PLAU (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7656713 | 0.72 | ABL1 (0.40) | ABL1MAOBTP53PPARDSMN1; SMN2 | |
| SCHEMBL7652482 | 0.71 | CHEK2 (0.47) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8154120 | 0.70 | ALOX5 (0.39) | ABL1CA12CA9 | |
| SCHEMBL7663316 | 0.69 | GABRA1 (0.45) | — | |
| SCHEMBL7657293 | 0.69 | UCHL1 (0.46) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |