Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669697 | 0.89 | MAPK13 (0.40) | F2PRSS1ALDH1A1HPGDRAB9A | |
| SCHEMBL6565690 | 0.85 | PLAU (0.54) | F2F10PLGPLAUPLAT | |
| SCHEMBL6565262 | 0.85 | ALDH1A1 (0.45) | F2F10PLAUPRSS1ALDH1A1 | |
| SCHEMBL6564223 | 0.84 | VNN1 (0.41) | F2PLGPLAUPRSS1ALDH1A1 | |
| SCHEMBL6563625 | 0.83 | PRSS1 (0.43) | F2F10PRSS1ALDH1A1HPGD | |
| SCHEMBL6563277 | 0.81 | F2 (0.41) | F2F10PLGPLAUPLAT | |
| SCHEMBL7671074 | 0.80 | F10 (0.43) | F2F10PRSS1ALDH1A1HPGD | |
| SCHEMBL6561921 | 0.79 | MAPK13 (0.45) | ALDH1A1HPGDRAB9AL3MBTL1LMNA | |
| SCHEMBL6561914 | 0.78 | GRM5 (0.43) | F2KLK1KLK5PRSS1ALDH1A1 | |
| SCHEMBL6563686 | 0.77 | F10 (0.46) | F10ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |