Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.57 |
| ▸ | HTR3A | P46098 | 7/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683751 | 0.81 | HTR1A (0.57) | HTR1AHRH3ALDH1A1CYP1A2DRD2 | |
| SCHEMBL7686113 | 0.79 | LMNA (0.51) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7684659 | 0.76 | MEN1 (0.54) | HTR1AALDH1A1DRD2DRD3 | |
| SCHEMBL7686048 | 0.75 | HTR7 (0.42) | HTR1AKDM4EDRD2HTR7 | |
| SCHEMBL7996580 | 0.74 | HTR1A (0.63) | HTR1AHTR3AHRH3KDM4EALDH1A1 | |
| SCHEMBL7687016 | 0.74 | HTR1A (0.53) | HTR1AHTR3ADRD2DRD3HTR7 | |
| SCHEMBL7686993 | 0.73 | DRD2 (0.46) | HTR1ADRD2DRD3HTR7 | |
| SCHEMBL7675521 | 0.73 | HRH4 (0.54) | HTR1AHRH3ALDH1A1HRH4DRD2 | |
| SCHEMBL3679755 | 0.72 | HTR1A (0.65) | HTR1AHTR3AHRH3KDM4EALDH1A1 | |
| SCHEMBL647772 | 0.72 | HTR1A (0.65) | HTR1AHTR3AHRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |