Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686993 | 0.79 | DRD2 (0.46) | DRD4DRD2DRD3HTR1A | |
| SCHEMBL7683751 | 0.79 | HTR1A (0.57) | DRD4DRD2DRD3HTR1AADRA1A | |
| SCHEMBL7686048 | 0.79 | HTR7 (0.42) | DRD2HTR1A | |
| SCHEMBL7686952 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2ADRD2DRD3TP53 | |
| SCHEMBL7686047 | 0.76 | HTR1A (0.57) | DRD2DRD3HTR1AALDH1A1 | |
| SCHEMBL7687016 | 0.74 | HTR1A (0.53) | DRD2DRD3HTR1AADRA1AADRA1B | |
| SCHEMBL7685522 | 0.74 | HTR7 (0.48) | DRD4DRD2DRD3HTR1AADRA1A | |
| SCHEMBL7683519 | 0.73 | DRD2 (0.43) | DRD2HTR1AADRA1AADRA1B | |
| SCHEMBL7683742 | 0.72 | DRD2 (0.48) | DRD2DRD3HTR1A | |
| SCHEMBL7686113 | 0.71 | LMNA (0.51) | MEN1KMT2ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |