Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | HTR2A | P28223 | 9/20 | 0.46 |
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | HTR7 | P34969 | 8/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683519 | 0.92 | DRD2 (0.43) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7684659 | 0.79 | MEN1 (0.54) | DRD2HTR1ADRD4DRD3 | |
| SCHEMBL7686952 | 0.78 | ALDH1A1 (0.51) | DRD2DRD3 | |
| SCHEMBL7683751 | 0.77 | HTR1A (0.57) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7686048 | 0.77 | HTR7 (0.42) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7687016 | 0.76 | HTR1A (0.53) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7685522 | 0.76 | HTR7 (0.48) | DRD2HTR1AHTR7DRD4DRD3 | |
| SCHEMBL7686047 | 0.73 | HTR1A (0.57) | DRD2HTR1AHTR7DRD3 | |
| SCHEMBL7683742 | 0.72 | DRD2 (0.48) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL14591333 | 0.71 | HTR1A (0.54) | DRD2HTR2AHTR1AHTR6DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |