Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702272 | 0.82 | HTR7 (0.39) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL4462321 | 0.78 | NPC1 (0.41) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL5140754 | 0.76 | NPC1 (0.40) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL16096838 | 0.72 | NPC1 (0.40) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL6129732 | 0.71 | PNMT (0.37) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL5500788 | 0.71 | NPC1 (0.36) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL26434306 | 0.70 | PNMT (0.49) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL20920147 | 0.69 | RAB9A (0.47) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL21046174 | 0.68 | HTR2B (0.49) | HTR7HTR2BNPC1RAB9APNMT | |
| SCHEMBL2233833 | 0.68 | RAB9A (0.46) | HTR7HTR2BNPC1RAB9APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342582-B1 | PURIFICATION AND/OR BIOSYNTHESIS OF OLIGOPEPTIDES IN PRESENCE OF A PHENOL OR MIXTURE; DEBLOCKING, AMIDATION; VACCINES, DRUGS, FOOD, AGRICULTURE | RHODIA CHIMIE (FR) | 2002-01-29 | — | — | US | disclosed |
| US-5798443-A | MEDIUM COMPRISING WATER IMMISCIBLE DILUENT AND HYDROXYAROMATIC COMPOUND | RHONE-POULENC CHIMIE (FR) | 1998-08-25 | — | — | US | disclosed |