Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708889 | 0.85 | DRD2 (0.38) | L3MBTL1TAS1R3TAS1R1TAS1R2EPHX1 | |
| SCHEMBL7708915 | 0.77 | ACHE (0.36) | KDM4EALDH1A1HPGDHSD17B10EPHX1 | |
| SCHEMBL7708957 | 0.75 | TAS1R3 (0.31) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7708985 | 0.71 | PTGS2 (0.44) | ALDH1A1CCR2PTGS1PTGS2 | |
| SCHEMBL10750917 | 0.70 | KDM4E (0.38) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10755491 | 0.69 | ALDH1A1 (0.37) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6951486 | 0.67 | RXRB (0.38) | KDM4EPTGS2SMN1; SMN2 | |
| SCHEMBL7708884 | 0.67 | SRD5A1 (0.40) | PTGS1PTGS2 | |
| SCHEMBL7708991 | 0.67 | NOTUM (0.35) | TAS1R3TAS1R1TAS1R2ALDH1A1HPGD | |
| SCHEMBL415651 | 0.67 | HTR2C (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |