Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714688 | 0.88 | PTGS2 (0.41) | PTGS2ACHEPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL7716874 | 0.76 | TMPRSS2 (0.30) | PTGS2 | |
| SCHEMBL7708884 | 0.75 | SRD5A1 (0.40) | PTGS2PTGS1SRD5A1NOTUM | |
| SCHEMBL7716876 | 0.75 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL24076754 | 0.73 | PTGS2 (0.44) | PTGS2ALDH1A1 | |
| SCHEMBL7708915 | 0.71 | ACHE (0.36) | ACHEALDH1A1NOTUMCCR2 | |
| SCHEMBL7708902 | 0.71 | L3MBTL1 (0.36) | PTGS2PTGS1ALDH1A1CCR2 | |
| SCHEMBL10352783 | 0.67 | CCR5 (0.39) | ALDH1A1NOTUM | |
| SCHEMBL9526750 | 0.67 | PTGS2 (0.46) | PTGS2PTGS1ALDH1A1CSNK2A1MEN1 | |
| SCHEMBL6958447 | 0.67 | SRC (0.40) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |