Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708991 | 0.84 | NOTUM (0.35) | HCAR2NOTUMALDH1A1HPGDFFAR1 | |
| SCHEMBL7708902 | 0.77 | L3MBTL1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10EPHX1 | |
| SCHEMBL7708985 | 0.71 | PTGS2 (0.44) | ACHENOTUMALDH1A1CCR2 | |
| SCHEMBL7712840 | 0.70 | TSHR (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL31381442 | 0.68 | ALDH1A1 (0.39) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7708884 | 0.67 | SRD5A1 (0.40) | NOTUMHTR2CHTR2B | |
| SCHEMBL413037 | 0.67 | ADRA2A (0.49) | ACHEALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL8693355 | 0.65 | ACHE (0.69) | ACHEKDM4EMAPTADRA2AADRA2B | |
| SCHEMBL5145610 | 0.63 | HCAR2 (0.40) | HCAR2NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL14345575 | 0.63 | DDB1 (0.37) | HCAR2NOTUMALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |