SCHEMBL9010795

SCHEMBL9010795

Cc1ccc(C(=O)C(=[N+]=[N-])S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
HTT P42858 2/20 0.44
POLB P06746 1/20 0.44
NOD2 Q9HC29 1/20 0.44
RECQL P46063 1/20 0.41
HSD11B1 P28845 1/20 0.41
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.40
PAX8 Q06710 1/20 0.40
ADAM17 P78536 1/20 0.40
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010901 0.93 KMT2A (0.51) CES2CES1ALDH1A1LMNAHTT
SCHEMBL6932211 0.93 CES2 (0.56) CES2CES1ALDH1A1LMNAHTT
SCHEMBL384366 0.92 CES2 (0.51) CES2CES1ALDH1A1LMNAHTT
SCHEMBL384364 0.92 CES2 (0.51) CES2CES1ALDH1A1LMNAHTT
SCHEMBL9010786 0.90 ALDH1A1 (0.52) CES2CES1ALDH1A1LMNAHTT
SCHEMBL9010805 0.89 CYP11B1 (0.43) CES2CES1ALDH1A1LMNAHTT
SCHEMBL7697548 0.88 MMP2 (0.39) CES2CES1ALDH1A1LMNAHTT
SCHEMBL7722385 0.88 LMNA (0.51) CES2CES1ALDH1A1LMNAHTT
SCHEMBL7697516 0.85 MMP2 (0.42) CES2CES1ALDH1A1LMNAHTT
SCHEMBL9010783 0.85 ALDH1A1 (0.47) ALDH1A1LMNAPOLBNOD2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417556-B1 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AG (DE) 1996-12-11 EP disclosed
EP-0444493-B1 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AG (DE) 1996-11-20 EP disclosed
US-5424166-A Negative-working radiation-sensitive mixture containing diazomethane acid generator and a radiation-sensitive recording material produced therfrom HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
US-5340682-A Sensitive, heat resistant, noncorrosive HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-23 US disclosed
EP-0444493-A2 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-04 EP disclosed
EP-0417556-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed