Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC3R | P41968 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733828 | 0.91 | DAGLA (0.38) | ZAP70SRCCTSCLTA4HDAGLA | |
| Trifluoroacetic Acid SCHEMBL7732324 | 0.88 | SLC7A11 (0.37) | ZAP70SRCSLC7A11PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7732364 | 0.88 | PRSS1 (0.40) | ZAP70SRCPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7731056 | 0.80 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.79 | CCR3 (0.41) | ZAP70SRCPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7733824 | 0.79 | MMP2 (0.39) | ZAP70SRCCTSCLTA4HDAGLA | |
| SCHEMBL7730721 | 0.78 | LTA4H (0.40) | ZAP70SRCLTA4H | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.73 | RAB9A (0.41) | HDAC1HDAC8 | |
| SCHEMBL7735549 | 0.72 | LTA4H (0.38) | ZAP70SRCHDAC1LTA4H | |
| SCHEMBL7861009 | 0.71 | MMP2 (0.40) | PRSS1PRSS2PRSS3TPSAB1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |