Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733848 | 0.90 | LMNA (0.38) | LNPEPERAP2RAB9AERAP1NPC1 | |
| SCHEMBL7734185 | 0.90 | LNPEP (0.34) | LNPEPERAP2ERAP1CHRNB2CHRNB4 | |
| SCHEMBL7731113 | 0.89 | PRSS8 (0.34) | LNPEPERAP2ERAP1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.87 | CTSL (0.41) | CTSLCTSBCTSSCTSKLNPEP | |
| SCHEMBL7723243 | 0.86 | CTSL (0.43) | CTSLCTSBCTSSCTSKLNPEP | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.77 | LMNA (0.39) | LNPEPERAP2ERAP1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.76 | OPRK1 (0.37) | CTSLCTSBLNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.76 | MMP2 (0.38) | CTSLLNPEPERAP2ERAP1MMP2 | |
| SCHEMBL7734127 | 0.76 | CYP3A4 (0.38) | LNPEPERAP2ERAP1MMP2 | |
| SCHEMBL7723159 | 0.76 | HDAC3 (0.35) | LNPEPMMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |