Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732452 | 0.95 | LMNA (0.42) | LMNAKMT2AMMP2METAP2TP53 | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.90 | MMP2 (0.38) | MMP2HDAC8HDAC1ERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.89 | CTSL (0.41) | MMP2ERAP2ERAP1LNPEPCTSC | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.89 | OPRK1 (0.37) | MMP2METAP2ERAP2ERAP1LNPEP | |
| SCHEMBL7733848 | 0.87 | LMNA (0.38) | LMNAKMT2ATP53SMN1; SMN2P2RY14 | |
| SCHEMBL7723243 | 0.85 | CTSL (0.43) | MMP2METAP2ERAP2ERAP1LNPEP | |
| SCHEMBL7730106 | 0.83 | CTSC (0.38) | MMP2METAP2TP53SMN1; SMN2ERAP2 | |
| Trifluoroacetic Acid SCHEMBL7731949 | 0.83 | FAAH (0.40) | MMP2ERAP2ERAP1LNPEPCTSC | |
| SCHEMBL7733852 | 0.78 | LMNA (0.37) | LMNAKMT2AMETAP2TP53SMN1; SMN2 | |
| SCHEMBL7731113 | 0.77 | PRSS8 (0.34) | MMP2XDHHDAC8HDAC1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |