Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7733845 | 0.95 | LMNA (0.39) | LMNAKMT2AMETAP2TP53SMN1; SMN2 | |
| SCHEMBL7730106 | 0.88 | CTSC (0.38) | METAP2TP53SMN1; SMN2MMP2CTSC | |
| SCHEMBL7723243 | 0.87 | CTSL (0.43) | METAP2MMP2CTSCERAP2ERAP1 | |
| SCHEMBL7733848 | 0.85 | LMNA (0.38) | LMNAKMT2ATP53SMN1; SMN2CETP | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.84 | MMP2 (0.38) | HDAC8HDAC1MMP2CTSCERAP2 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.84 | CTSL (0.41) | MMP2CTSCERAP2ERAP1LNPEP | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.83 | OPRK1 (0.37) | METAP2MMP2CTSCERAP2ERAP1 | |
| SCHEMBL7723017 | 0.80 | LMNA (0.45) | LMNAKMT2ATP53SMN1; SMN2CETP | |
| SCHEMBL7858147 | 0.78 | XDH (0.46) | LMNAKMT2AMETAP2TP53SMN1; SMN2 | |
| SCHEMBL7736136 | 0.78 | XDH (0.46) | LMNAKMT2AMETAP2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |