Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734862 | 0.79 | SLC22A12 (0.41) | ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL7724872 | 0.74 | GAA (0.36) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL7735189 | 0.74 | GAA (0.36) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL11642466 | 0.70 | MAOA (0.56) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL7734855 | 0.66 | SIRT2 (0.34) | KMT2AMEN1AKR1B1 | |
| SCHEMBL7737446 | 0.66 | PGK1 (0.35) | ALDH1A1KMT2AMEN1AKR1B1 | |
| SCHEMBL7733878 | 0.65 | RAB9A (0.43) | POLBNPC1RAB9AAKR1B1 | |
| SCHEMBL1679090 | 0.64 | CXCL8 (0.56) | ALDH1A1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL6612158 | 0.63 | MAOA (0.62) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL1262377 | 0.62 | PTGS2 (0.43) | KMT2AMEN1MAPTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |