Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15199188 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NPC1EPHX1KDM4EALOX15 | |
| SCHEMBL17208385 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NPC1EPHX1KDM4EALOX15 | |
| SCHEMBL13267738 | 0.93 | ALDH1A1 (0.36) | ALDH1A1NPC1EPHX1KDM4EALOX15 | |
| SCHEMBL256670 | 0.89 | — | — | |
| SCHEMBL14188604 | 0.83 | ALDH1A1 (0.37) | ALDH1A1NPC1EPHX1KDM4EALOX15 | |
| SCHEMBL13018343 | 0.82 | ALDH1A1 (0.34) | ALDH1A1NPC1EPHX1KDM4EALOX15 | |
| SCHEMBL256032 | 0.81 | — | — | |
| SCHEMBL2128026 | 0.81 | — | — | |
| SCHEMBL27787478 | 0.81 | TDP1 (0.33) | ALDH1A1MAPTSMN1; SMN2TDP1FFAR3 | |
| SCHEMBL4433068 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPC1EPHX1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207267-A1 | (R)-Glutarimide CRBN Ligands and Methods of Use | BEIGENE SWITZERLAND GMBH (CH) | 2024-06-27 | — | — | US | disclosed |
| US-10039843-B2 | Paramagnetic solid lipid nanoparticles (pSLNs) containing metal amphiphilic complexes for MRI | BRACCO IMAGING S.P.A. (IT) | 2018-08-07 | — | — | US | disclosed |
| US-9981046-B2 | Drug-conjugates, conjugation methods, and uses thereof | Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) | 2018-05-29 | — | — | US | disclosed |
| US-9867811-B2 | Method of treating atherosclerosis in high triglyceride subjects | NOVARTIS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| CN-105073746-B | Substituted imidazopyridines as HDM2 inhibitors | 默沙东公司 | 2017-03-22 | — | — | CN | disclosed |
| US-20160067350-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | Concortis Biosystems, Corp., a wholly owned Subsidiary of Sorrento Therapeutics, Inc. (US) | 2016-03-10 | — | — | US | disclosed |
| US-9259491-B2 | Class of diazepine derivative chelating agents and complexes with paramagnetic metals thereof as MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2016-02-16 | — | — | US | disclosed |
| CN-105073746-A | Substituted imidazopyridines as HDM2 inhibitors | MERCK SHARP & DOHME | 2015-11-18 | — | — | CN | disclosed |
| US-20150258221-A1 | Paramagnetic Solid Lipid Nanoparticles (pSLNs) Containing Metal Amphiphilic Complexes For MRI | BRACCO IMAGING S.P.A. (IT) | 2015-09-17 | — | — | US | disclosed |
| US-20150037261-A1 | New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents | BRACCO IMAGING S.P.A. (IT) | 2015-02-05 | — | — | US | disclosed |
| US-20140031334-A1 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-8507647-B2 | Antibacterial agents for the treatment of gram positive infections | CUBIST PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-8481042-B2 | Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents | SANOFI (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20120244172-A1 | Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
| US-8071600-B2 | Derivatives of 4-piperazin-1-yl-4-benzo[B]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-12-06 | — | — | US | disclosed |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-6414031-B1 | CONTROLLING FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |
| CN-1301249-A | Bisoximether derivatives, methods and intermediate products for the production thereof, and their use for combating fungicidal pests and animal pests | BASF AG (DE) | 2001-06-27 | — | — | CN | disclosed |
| EP-1077953-A2 | BISOXIMETHER DERIVATIVES, METHODS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF, AND THEIR USE FOR COMBATING FUNGICIDAL PESTS AND ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059982-A2 | BISOXIMETHER DERIVATIVES, INTERMEDIATE PRODUCTS, AND THEIR USE FOR COMBATING FUNGICIDAL PESTS AND ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150037261-A1 | New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents | BAZ2A, BAZ2B, BAZ1A | ALDH1A1 4327/4885NPC1 2113/4885EPHX1 3360/4885 |
| US-10039843-B2 | Paramagnetic solid lipid nanoparticles (pSLNs) containing metal amphiphilic complexes for MRI | PLIN3, PEX3, SLC39A3 | ALDH1A1 4600/4885NPC1 161/4885EPHX1 3064/4885 |
| US-20160067350-A1 | Drug-Conjugates, Conjugation Methods, and Uses Thereof | PAICS, CES2, DNPEP | ALDH1A1 160/4885NPC1 635/4885EPHX1 550/4885 |
| US-20140031334-A1 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | GRIN2C, GRIN2B, PMP22 | ALDH1A1 408/4885NPC1 436/4885EPHX1 2961/4885 |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | ALDH1A1 4703/4885NPC1 2676/4885EPHX1 3837/4885 |
| US-20240207267-A1 | (R)-Glutarimide CRBN Ligands and Methods of Use | CRBN, CDR2, CRKL | ALDH1A1 2445/4885NPC1 4014/4885EPHX1 3672/4885 |
| US-20120244172-A1 | Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents | GABRA4, GABRA1, GABRA2 | ALDH1A1 908/4885NPC1 2597/4885EPHX1 2213/4885 |
| US-20150258221-A1 | Paramagnetic Solid Lipid Nanoparticles (pSLNs) Containing Metal Amphiphilic Complexes For MRI | PLIN3, PEX3, SLC39A3 | ALDH1A1 4600/4885NPC1 161/4885EPHX1 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.