Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810764 | 0.84 | HDAC4 (0.47) | BRD4HDAC4HDAC7HDAC5FFAR2 | |
| SCHEMBL2542929 | 0.84 | HDAC4 (0.47) | BRD4HDAC4HDAC7HDAC5FFAR2 | |
| SCHEMBL8684068 | 0.82 | ALDH1A1 (0.46) | POLBALDH1A1FFAR1GAALMNA | |
| SCHEMBL4169154 | 0.81 | CYP1A2 (0.48) | POLBALDH1A1 | |
| SCHEMBL1720514 | 0.81 | LMNA (0.51) | HDAC4HDAC7HDAC5ALDH1A1FFAR1 | |
| SCHEMBL6802464 | 0.81 | HDAC4 (0.44) | BRD4HDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL6049547 | 0.81 | BRD4 (0.36) | BRD4S1PR3ALDH1A1GAATSHR | |
| SCHEMBL5199206 | 0.80 | L3MBTL1 (0.49) | BRD4HDAC4HDAC7HDAC5FFAR2 | |
| SCHEMBL10686874 | 0.80 | BRD4 (0.41) | BRD4HDAC4HDAC7HDAC5FFAR2 | |
| SCHEMBL4735057 | 0.80 | BRD4 (0.41) | BRD4HDAC4HDAC7HDAC5FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153674-B | Iminothiadiazine dioxide derivatives as inhibitors of plasmepsin V of plasmodium | UCB生物制药有限责任公司 | 2022-03-22 | — | — | CN | disclosed |
| US-11136310-B2 | Iminotetrahydropyrimidinone derivatives as plasmepsin V inhibitors | UCB Biopharma SRL (BE) | 2021-10-05 | — | — | US | disclosed |
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | disclosed |
| US-10953012-B2 | Heterocyclic compounds for the inhibition of pask | BIOENERGENIX LLC (US) | 2021-03-23 | — | — | US | disclosed |
| US-10953012-B2 | Heterocyclic compounds for the inhibition of pask | BIOENERGENIX LLC (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200283416-A1 | IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS | CELLTECH R&D LIMITED (GB) | 2020-09-10 | — | — | US | disclosed |
| EP-3380464-B1 | IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS | UCB Biopharma SRL (BE) | 2020-05-27 | — | — | EP | disclosed |
| US-10464932-B2 | Iminothiadiazinane dioxide derivatives as plasmepsin V inhibitors | UCB BIOPHARMA SPRL (BE) | 2019-11-05 | — | — | US | disclosed |
| US-20190040053-A1 | Iminothiadiazinane Dioxide Derivatives as Plasmepsin V Inhibitors | UCB BIOPHARMA SPRL (BE) | 2019-02-07 | — | — | US | disclosed |
| EP-3419975-A1 | IMINOTHIADIAZINANE DIOXIDE DERIVATIVES AS PLASMEPSIN V INHIBITORS | UCB Biopharma SPRL (BE) | 2019-01-02 | — | — | EP | disclosed |
| WO-2012149157-A2 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012149157-A2 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | WO | disclosed |
| US-6417386-B2 | HYDRAZONE DERIVATIVES; ACARINA; MITICIDES | SYNGENTA CROP PROTECTION, INC. | 2002-07-09 | — | — | US | disclosed |
| US-20010039247-A1 | Pesticidal compositions | KARRER FRIEDRICH (CH) | 2001-11-08 | — | — | US | disclosed |
| US-6306798-B1 | Compounds for controlling insects and representatives of the order acarina | SYNGENTA CROP PROTECTION, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-1021398-A1 | PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2000-07-26 | — | — | EP | disclosed |
| CN-1226230-A | Pesticidal composition | NOVARTIS AG (CH) | 1999-08-18 | — | — | CN | disclosed |
| WO-1998003475-A1 | PESTICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | disclosed |
| US-4076530-A | Dry photographic copying method for producing Te images | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283416-A1 | IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS | PEPD, ADAM17, ANPEP | BRD4 796/4885HDAC4 1537/4885HDAC7 2378/4885 |
| US-10464932-B2 | Iminothiadiazinane dioxide derivatives as plasmepsin V inhibitors | PEPD, CTSL, SERPINE1 | BRD4 1112/4885HDAC4 1197/4885HDAC7 1775/4885 |
| US-11136310-B2 | Iminotetrahydropyrimidinone derivatives as plasmepsin V inhibitors | PEPD, ADAM17, ANPEP | BRD4 796/4885HDAC4 1537/4885HDAC7 2378/4885 |
| US-10953012-B2 | Heterocyclic compounds for the inhibition of pask | PASK, PDXK, PANK2 | BRD4 649/4885HDAC4 592/4885HDAC7 515/4885 |
| US-20010039247-A1 | Pesticidal compositions | MTX1, PEF1, ECH1 | BRD4 4451/4885HDAC4 3442/4885HDAC7 2596/4885 |
| US-20190040053-A1 | Iminothiadiazinane Dioxide Derivatives as Plasmepsin V Inhibitors | PEPD, CTSL, SERPINE1 | BRD4 1112/4885HDAC4 1197/4885HDAC7 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.