Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Etidronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 15/20 | 0.47 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.33 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.33 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | PGK2 | P07205 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etidronic Acid SCHEMBL3897758 | 0.97 | LMNA (0.87) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL6850113 | 0.97 | LMNA (0.87) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL18607 | 0.96 | LMNA (1.00) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10532992 | 0.96 | LMNA (1.00) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL1924063 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10524952 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL17580248 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL6141145 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10706705 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL3896726 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377635-B2 | Flow cell systems and methods | NAUTILUS SUBSIDIARY, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-12306093-B2 | Methods and systems for integrated on-chip single-molecule detection | NAUTILUS SUBSIDIARY, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| EP-4547389-A2 | FUNCTIONALIZED MATERIALS FOR CARBON DIOXIDE CAPTURE AND SYSTEMS THEREOF | X Development LLC (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-118891028-A | Oral care compositions, methods and kits | 舒万诺知识产权公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2024006521-A2 | FUNCTIONALIZED MATERIALS FOR CARBON CAPTURE AND SYSTEMS THEREOF | X DEVELOPMENT LLC (US) | 2024-01-04 | — | — | WO | disclosed |
| US-11850575-B2 | Doped graphitic carbon nitrides, methods of making and uses of the same | THE GEORGE WASHINGTON UNIVERSITY (US) | 2023-12-26 | — | — | US | disclosed |
| US-20230221243-A1 | METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION | NAUTILUS SUBSIDIARY, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230213438-A1 | METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION | NAUTILUS SUBSIDIARY, INC. | 2023-07-06 | — | — | US | disclosed |
| EP-3233940-B1 | PHOTOCROSSLINKABLE BLOCK COPOLYMERS FOR HOT-MELT ADHESIVES | HENKEL AG & CO KGAA (DE) | 2023-04-19 | — | — | EP | disclosed |
| US-20220379582-A1 | FLOW CELL SYSTEMS AND METHODS | NAUTILUS SUBSIDIARY, INC. | 2022-12-01 | — | — | US | disclosed |
| US-20170232427-A1 | DOPED GRAPHITIC CARBON NITRIDES, METHODS OF MAKING AND USES OF THE SAME | THE GEORGE WASHINGTON UNIVERSITY (US) | 2017-08-17 | — | — | US | disclosed |
| US-9587062-B2 | Photocrosslinkable block copolymers for hot-melt adhesives | Henkel IP & Holding GmbH and Henkel AG & Co. KGaA (DE) | 2017-03-07 | — | — | US | disclosed |
| WO-2016100251-A1 | PHOTOCROSSLINKABLE BLOCK COPOLYMERS FOR HOT-MELT ADHESIVES | Henkel IP & Holding GmbH (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-20160168298-A1 | PHOTOCROSSLINKABLE BLOCK COPOLYMERS FOR HOT-MELT ADHESIVES | HENKEL AG & CO. KGAA (DE) | 2016-06-16 | — | — | US | disclosed |
| CN-102735788-B | Method for analyzing and measuring etidronic acid and salts of etidronic acid in sample | CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-102735788-A | Method for analyzing and measuring etidronic acid and salts of etidronic acid in sample | CHINESE ACAD INSP & QUARANTINE | 2012-10-17 | — | — | CN | disclosed |
| WO-2001014639-A1 | USE OF DIELS-ALDER ADDUCTS FOR PRODUCING PAPER | NOPCO PAPER TECHNOLOGY HOLDING AS (NO) | 2001-03-01 | — | — | WO | disclosed |
| US-6140033-A | SUPPORT WITH SILVER HALIDE EMULSIONS WITH COUPLERS | EASTMAN KODAK COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-6071686-A | Photographic element containing pyrazoloazole coupler and a specific anti-fading combination | EASTMAN KODAK COMPANY (US) | 2000-06-06 | — | — | US | disclosed |
| US-5424176-A | Acceleration of silver removal by thioether compounds in sulfite fixer | EASTMAN KODAK COMPANY (US) | 1995-06-13 | — | — | US | disclosed |