SCHEMBL775157

SCHEMBL775157

[O-][S+](c1ccccc1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
KIF11 P52732 1/20 0.32
CES1 P23141 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL10432095 0.89 CA12 (0.46) TSHRALDH1A1KIF11CES1
SCHEMBL776744 0.80 ALDH1A1 (0.35) TSHRALDH1A1KIF11
SCHEMBL775529 0.80 ALDH1A1 (0.35) TSHRALDH1A1KIF11
SCHEMBL7929166 0.77 CA1 (0.32)
SCHEMBL13703265 0.77 NR1H2 (0.31)
SCHEMBL775604 0.77 NR1H2 (0.32) TSHRALDH1A1
SCHEMBL11659804 0.76 TSHR (0.33) TSHRALDH1A1
SCHEMBL7651489 0.75 LMNA (0.38) TSHRALDH1A1
SCHEMBL17288700 0.75
SCHEMBL7940657 0.75 ESR1 (0.39) TSHRALDH1A1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250242340-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-07-31 US claimed
US-20250163014-A1 PRODUCTION METHOD FOR EPISULFIDE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-22 US claimed
EP-4504404-A2 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-02-12 EP claimed
EP-4491621-A1 PRODUCTION METHOD FOR EPISULFIDE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-01-15 EP claimed
CN-119300914-A SABRE catalysts containing fluorinated carbon chains for delivery of metal-free MRI contrast agents 美国卫生和人力服务部 2025-01-10 CN claimed
CN-118829634-A Method for producing episulfide compound 三菱瓦斯化学株式会社 2024-10-22 CN claimed
US-20240216900-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-07-04 US claimed
WO-2023196594-A2 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO claimed
US-7087789-B2 Methods for nucleophilic fluoromethylation UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2006-08-08 US claimed
US-20040230079-A1 Methods for nucleophilic fluoromethylation SOUTHERN CALIFORNIA, UNIVERSITY OF 2004-11-18 US claimed
WO-2004063129-A2 METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2004-07-29 WO claimed
US-6215021-B1 TRIFLUOROMETHYL DIPHENYLSULFONIUM TRIFLATE DERIVATIVES IDAHO RESEARCH FOUNDATION, INC. 2001-04-10 US claimed
US-4659720-A POULTRY ANTIPROTOZOA AGENT MERCK & CO., INC. (US) 1987-04-21 US claimed
EP-0113570-B1 5-(AMINO OR SUBSTITUTED AMINO) IMIDAZOLES MERCK & CO. INC. (US) 1987-02-25 EP claimed
US-4622330-A Antiprotozoal 3-amino or substituted amino pyrazoles MERCK & CO., INC. (US) 1986-11-11 US claimed
EP-0113570-A1 5-(Amino or substituted amino) imidazoles MERCK & CO. INC. (US) 1984-07-18 EP claimed
US-20250242340-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-07-31 US disclosed
US-20250244419-A1 INFUSION DEVICE FOR THE PREPARATION AND DELIVERY OF MRI PROBES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-07-31 US disclosed
US-4622330-A Antiprotozoal 3-amino or substituted amino pyrazoles MERCK & CO., INC. (US) 1986-11-11 US disclosed
EP-0113570-A1 5-(Amino or substituted amino) imidazoles MERCK & CO. INC. (US) 1984-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250244419-A1 INFUSION DEVICE FOR THE PREPARATION AND DELIVERY OF MRI PROBES MPI, HAMP, HIF1A TSHR 1785/4885ALDH1A1 3474/4885KIF11 1430/4885
US-20040230079-A1 Methods for nucleophilic fluoromethylation PHF2, HAO2, GSTM2 TSHR 2421/4885ALDH1A1 1240/4885KIF11 4359/4885
US-20240216900-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS FABP7, FFAR1, FABP1 TSHR 112/4885ALDH1A1 4484/4885KIF11 1187/4885
US-20250242340-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS FABP7, FFAR1, FABP1 TSHR 112/4885ALDH1A1 4484/4885KIF11 1187/4885
US-20250163014-A1 PRODUCTION METHOD FOR EPISULFIDE COMPOUND SULT1E1, ESR2, MRPL21 TSHR 2688/4885ALDH1A1 2081/4885KIF11 2499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.