Lithium

Lithium

SCHEMBL775306

CC(C)(C)OC(C)(C)C.[Li]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28365346 0.94 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL8913 0.94
Potassium SCHEMBL183183 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Water SCHEMBL28793234 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL28408785 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Methane SCHEMBL30637 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Water SCHEMBL8067978 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL31678023 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Ethane SCHEMBL353672 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL30933076 0.89 ALDH1A1 (0.42) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993010076-A1 SYNTHESIS AND OPTICAL RESOLUTION OF THE TAXOL SIDE CHAIN AND RELATED COMPOUNDS THE UNIVERSITY OF MISSISSIPPI (US) 1993-05-27 WO claimed
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 US disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 US disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 US disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 US disclosed
US-20210403427-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2021-12-30 US disclosed
EP-3854786-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API Corporation (JP) 2021-07-28 EP disclosed
WO-2020059891-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES 株式会社エーピーアイ コーポレーション 2020-03-26 WO disclosed
US-20120071651-A1 Processes for Preparing 1,2-Substituted Cyclopropyl Derivatives ABBOTT LABORATORIES (US) 2012-03-22 US disclosed
US-20060183758-A1 Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans CB RESEARCH AND DEVELOPMENT, INC. (US) 2006-08-17 US disclosed
EP-1082316-B1 METHODS AND USEFUL INTERMEDIATES FOR PACLITAXEL SYNTHESIS FROM C-7, C-10 DI-CBZ BACCATIN III NAPRO BIOTHERAPEUTICS INC (US) 2004-06-23 EP disclosed
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed
US-6448417-B1 ESTERIFICATION OF C-7, C-10 DI-CBZ 10-DEACETYLBACCATIN III WITH AN N-CARBAMATE PROTECTED, C-2-PROTECTED 3-PHENYL ISOSERINE SIDE CHAIN NAPRO BIOTHERAPEUTICS, INC. 2002-09-10 US disclosed
EP-1082316-A1 METHODS AND USEFUL INTERMEDIATES FOR PACLITAXEL SYNTHESIS FROM C-7, C-10 DI-CBZ BACCATIN III NAPRO BIOTHERAPEUTICS, INC. (US) 2001-03-14 EP disclosed
US-6103842-A USING CATALYST SYSTEM FOR EXOTHERMAL POLYMERIZATION WHICH CONSISTS ESSENTIALLY OF (A) AN ORGANOLITHIUM COMPOUND, (B) A BARIUM ALKOXIDE AND (C) A LITHIUM ALKOXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-08-15 US disclosed
WO-1999057105-A1 METHODS AND USEFUL INTERMEDIATES FOR PACLITAXEL SYNTHESIS FROM C-7, C-10 DI-CBZ BACCATIN III NAPRO BIOTHERAPEUTICS, INC. (US) 1999-11-11 WO disclosed
EP-0877034-A1 Random trans SBR with low vinyl microstructure THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-11-11 EP disclosed
WO-1993010076-A1 SYNTHESIS AND OPTICAL RESOLUTION OF THE TAXOL SIDE CHAIN AND RELATED COMPOUNDS THE UNIVERSITY OF MISSISSIPPI (US) 1993-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403427-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGES2 ALDH1A1 1057/4885TSHR 3320/4885TDP1 3836/4885
US-20060183758-A1 Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans TPMT, INMT, AANAT ALDH1A1 426/4885TSHR 2250/4885TDP1 626/4885
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 ALDH1A1 1128/4885TSHR 3372/4885TDP1 3851/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 ALDH1A1 447/4885TSHR 3506/4885TDP1 4509/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 ALDH1A1 447/4885TSHR 3506/4885TDP1 4509/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 ALDH1A1 1057/4885TSHR 3320/4885TDP1 3836/4885
US-20120071651-A1 Processes for Preparing 1,2-Substituted Cyclopropyl Derivatives HRH3, HRH4, HRH1 ALDH1A1 1799/4885TSHR 736/4885TDP1 4217/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 ALDH1A1 1057/4885TSHR 3320/4885TDP1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.