Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898115 | 0.90 | OPRD1 (0.54) | OPRD1EP300PTPN1PTGS2ALDH1A1 | |
| SCHEMBL7760695 | 0.83 | OPRD1 (0.56) | OPRD1EP300PTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL7902764 | 0.77 | OPRD1 (0.54) | OPRD1EP300PTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL7756777 | 0.75 | OPRD1 (0.52) | OPRD1EP300PTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL11203493 | 0.74 | FFAR1 (0.51) | SMN1; SMN2SLC13A5 | |
| SCHEMBL7899189 | 0.74 | OPRD1 (0.51) | OPRD1EP300PTPN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7760707 | 0.74 | OPRD1 (0.50) | OPRD1EP300PTGS2KDM4EPKM | |
| SCHEMBL7760717 | 0.74 | OPRD1 (0.50) | OPRD1EP300PTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL678077 | 0.73 | ALOX5 (0.56) | OPRD1EP300PTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL5599629 | 0.73 | OPRD1 (0.53) | OPRD1EP300SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728755-B1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-11 | — | — | EP | disclosed |
| EP-0728755-A1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-08-28 | — | — | EP | disclosed |