Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763126 | 0.90 | OPRD1 (0.52) | OPRD1EP300KDM4EPKMHPGD | |
| SCHEMBL7760695 | 0.77 | OPRD1 (0.56) | OPRD1EP300KDM4EPKMHPGD | |
| SCHEMBL7902764 | 0.76 | OPRD1 (0.54) | OPRD1EP300KDM4EPKML3MBTL1 | |
| SCHEMBL7899189 | 0.75 | OPRD1 (0.51) | OPRD1EP300KDM4EHPGDL3MBTL1 | |
| SCHEMBL5599629 | 0.74 | OPRD1 (0.53) | OPRD1EP300KDM4EPKMHPGD | |
| SCHEMBL7756777 | 0.74 | OPRD1 (0.52) | OPRD1EP300KDM4EPKML3MBTL1 | |
| SCHEMBL7760707 | 0.73 | OPRD1 (0.50) | OPRD1EP300KDM4EPKML3MBTL1 | |
| SCHEMBL7760717 | 0.73 | OPRD1 (0.50) | OPRD1EP300KDM4EPKMMAPK14 | |
| SCHEMBL678077 | 0.72 | ALOX5 (0.56) | OPRD1EP300KDM4EPKMMAPK14 | |
| SCHEMBL7760704 | 0.71 | OPRD1 (0.49) | OPRD1EP300KDM4EPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37078-E1 | Thiophene compounds | ADIR ET COMPAGNIE (FR) | 2001-02-27 | — | — | US | disclosed |
| US-5705525-A | ANTIINFLAMMATORY AGENTS AND TREATMENT OF RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1998-01-06 | — | — | US | disclosed |