Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527174 | 1.00 | GPR3 (0.39) | GPR3MAPK1TSHRTAAR1ALDH1A1 | |
| Fluoride SCHEMBL775530 | 0.97 | GPR3 (0.38) | GPR3MAPK1TSHRTAAR1ALDH1A1 | |
| SCHEMBL7333621 | 0.80 | GPR3 (0.32) | GPR3MAPK1MEN1KMT2AKCNN4 | |
| SCHEMBL16469424 | 0.80 | GPR3 (0.32) | GPR3MAPK1 | |
| SCHEMBL16174370 | 0.77 | ACHE (0.40) | TSHRALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL16174416 | 0.77 | ACHE (0.40) | TSHRALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL16139498 | 0.77 | ACHE (0.40) | TSHRALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL11659804 | 0.76 | TSHR (0.33) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL20877679 | 0.76 | GPR3 (0.40) | GPR3TSHRALDH1A1 | |
| SCHEMBL20877639 | 0.76 | GPR3 (0.40) | GPR3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558862-B | Synthetic method and intermediate of anti-leukemia cancer cell active molecule | 上海工程技术大学 | 2020-07-17 | — | — | CN | claimed |
| CN-109956960-A | A kind of synthetic method of isothiourea class catalyst | 上海工程技术大学 | 2019-07-02 | — | — | CN | claimed |
| CN-108558862-A | A kind of synthetic method and intermediate of anti-leukocythemia tumor cell viability molecule | 上海工程技术大学 | 2018-09-21 | — | — | CN | claimed |
| CN-106892847-A | A kind of synthetic method of three (tert-butyl-phenyl) sulphur bromines | 西安瑞联新材料股份有限公司 | 2017-06-27 | — | — | CN | claimed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| US-20220149436-A1 | NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-05-12 | — | — | US | disclosed |
| US-11283107-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-03-22 | — | — | US | disclosed |
| US-11014955-B2 | Cyclic peroxides as prodrugs for selective delivery of agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200317714-A1 | CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-10-08 | — | — | US | disclosed |
| CN-108558862-B | Synthetic method and intermediate of anti-leukemia cancer cell active molecule | 上海工程技术大学 | 2020-07-17 | — | — | CN | disclosed |
| CN-108558862-B | Synthetic method and intermediate of anti-leukemia cancer cell active molecule | 上海工程技术大学 | 2020-07-17 | — | — | CN | disclosed |
| EP-3670496-A2 | ACC2 INHIBITORS | Shionogi&Co., Ltd. (JP) | 2020-06-24 | — | — | EP | disclosed |
| US-20080255384-A1 | THREE CARBON PRECURSOR SYNTHONS | NEW MEXICO HIGHLANDS UNIVERSITY | 2008-10-16 | — | — | US | disclosed |
| US-20080064659-A1 | EPOXYKETONE-BASED IMMUNOPROTEASOME INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2008-03-13 | — | — | US | disclosed |
| US-20070293682-A1 | Methods of Preparing Sulfinamides and Sulfoxides | APSINTERM, LLC | 2007-12-20 | — | — | US | disclosed |
| US-7256297-B2 | Methods of preparing sulfinamides and sulfoxides | APSINTERM, LLC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7064214-B2 | Methods of preparing sulfinamides and sulfoxides | APSINTERM LLC (US) | 2006-06-20 | — | — | US | disclosed |
| US-20060128767-A1 | Methods of preparing sulfinamides and sulfoxides | SENANAYAKE CHRIS H | 2006-06-15 | — | — | US | disclosed |
| CN-1659154-A | Process for the preparation of amine stereoisomers | APSINTERM LLC (US) | 2005-08-24 | — | — | CN | disclosed |
| US-20030083517-A1 | Methods of preparing sulfinamides and sulfoxides | APSINTERM LLC | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128767-A1 | Methods of preparing sulfinamides and sulfoxides | STS, TST, CBS | GPR3 4091/4885MAPK1 4052/4885TSHR 2609/4885 |
| US-20080064659-A1 | EPOXYKETONE-BASED IMMUNOPROTEASOME INHIBITORS | PSME2, PSMB2, PSME1 | GPR3 4833/4885MAPK1 3901/4885TSHR 4804/4885 |
| US-20070293682-A1 | Methods of Preparing Sulfinamides and Sulfoxides | STS, TST, CBS | GPR3 4091/4885MAPK1 4052/4885TSHR 2609/4885 |
| US-11014955-B2 | Cyclic peroxides as prodrugs for selective delivery of agents | GPX4, PRDX1, PRDX3 | GPR3 2559/4885MAPK1 3944/4885TSHR 1467/4885 |
| US-20080255384-A1 | THREE CARBON PRECURSOR SYNTHONS | MRPS23, DAP3, SPIN3 | GPR3 2056/4885MAPK1 919/4885TSHR 2794/4885 |
| US-20200317714-A1 | CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS | GPX4, PRDX1, GPX1 | GPR3 2552/4885MAPK1 3732/4885TSHR 1944/4885 |
| US-20030083517-A1 | Methods of preparing sulfinamides and sulfoxides | STS, TST, CBS | GPR3 4091/4885MAPK1 4052/4885TSHR 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.