SCHEMBL7770076

SCHEMBL7770076

Cc1cccc(NC(=O)Nc2ccc(S(=O)(=O)NC(=O)c3cccc(C)c3)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
KCNK3 O14649 2/20 0.56
KCNK9 Q9NPC2 2/20 0.56
KCNH2 Q12809 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
GHSR Q92847 1/20 0.55
SAE1 Q9UBE0 1/20 0.54
UBA2 Q9UBT2 1/20 0.54
LMNA P02545 1/20 0.54
GPR17 Q13304 2/20 0.54
IDO1 P14902 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
CSF1R P07333 1/20 0.53
FLT1 P17948 1/20 0.53
FLT3 P36888 1/20 0.53
NPC1 O15118 2/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8658342 0.94 LMNA (0.60) RAB9AKMT2AMEN1KCNK3KCNK9
SCHEMBL8667069 0.91 LMNA (0.60) RAB9AKMT2AMEN1RXFP1GHSR
SCHEMBL8655317 0.90 ALDH1A1 (0.56) RAB9AKMT2AMEN1KCNK3KCNK9
SCHEMBL9467745 0.90 LMNA (0.54) RAB9AKMT2AMEN1KCNK3KCNK9
SCHEMBL8664097 0.89 GPR27 (0.58) RAB9AKMT2AMEN1GHSRSAE1
SCHEMBL8668880 0.84 FLT1 (0.58) RAB9AKMT2AMEN1KCNK3KCNK9
SCHEMBL7776308 0.84 MAPT (0.61) KMT2AMEN1KCNK3KCNK9LMNA
SCHEMBL8658192 0.84 ALDH1A1 (0.56) RAB9AKMT2AMEN1LMNAGPR17
SCHEMBL9467928 0.84 GPR17 (0.52) RAB9AKCNK3KCNK9KCNH2RXFP1
SCHEMBL9179605 0.84 PTGS2 (0.64) KMT2AMEN1FLT1POLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed