Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643603 | 0.75 | PTGS2 (0.54) | LMNANPSR1AURKAKIF18AMAPT | |
| SCHEMBL7778323 | 0.74 | LMNA (0.42) | LMNANPSR1AURKAKIF18AMAPT | |
| SCHEMBL250144 | 0.72 | ALDH1A1 (0.80) | LMNANPSR1KIF18AMAPTTDP1 | |
| SCHEMBL8666593 | 0.72 | NPC1 (0.35) | PTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9840644 | 0.72 | KIF18A (0.51) | LMNANPSR1AURKAKIF18AMAPT | |
| SCHEMBL3296279 | 0.71 | ALDH1A1 (0.70) | LMNANPSR1MAPTPTGS2ALDH1A1 | |
| SCHEMBL10869745 | 0.70 | ALDH1A1 (0.68) | KIF18APTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7782970 | 0.70 | ALDH1A1 (0.43) | LMNANPSR1MAPTTDP1PTGS2 | |
| SCHEMBL27733606 | 0.69 | ALDH1A1 (0.73) | LMNANPSR1KIF18AMAPTTDP1 | |
| SCHEMBL9473123 | 0.69 | HTR6 (0.53) | LMNANPSR1AURKAKIF18AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |