Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803961 | 0.78 | AGTR1 (0.51) | AGTR2AGTR1OPRM1OPRK1 | |
| SCHEMBL7803777 | 0.76 | AGTR1 (0.45) | AGTR2AGTR1 | |
| SCHEMBL8317959 | 0.70 | OXTR (0.36) | OXTR | |
| SCHEMBL24581535 | 0.70 | TNK2 (0.37) | OXTR | |
| SCHEMBL6151300 | 0.68 | LTA4H (0.43) | OPRM1OPRK1 | |
| SCHEMBL7137362 | 0.67 | GAA (0.35) | — | |
| SCHEMBL8323062 | 0.67 | OXTR (0.39) | OXTR | |
| SCHEMBL11772440 | 0.67 | ABCB11 (0.39) | — | |
| SCHEMBL7799808 | 0.67 | ALDH1A1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL13564558 | 0.67 | HPGD (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749964-B1 | N-Heterocyclyl biphenyl sulfonamides | ASTRAZENECA AB (SE) | 2001-10-04 | — | — | EP | disclosed |
| EP-0749964-A1 | N-Heterocyclyl biphenyl sulfonamides | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |