Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811933 | 0.80 | EGLN1 (0.37) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL6170009 | 0.75 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL6170922 | 0.75 | ALDH1A1 (0.47) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL6170913 | 0.73 | KMO (0.48) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL6172328 | 0.73 | TSPO (0.54) | RAB9AALDH1A1NPC1KDM4EMEN1 | |
| SCHEMBL6170872 | 0.72 | TDP1 (0.46) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL6169951 | 0.71 | TSPO (0.46) | RAB9AALDH1A1NPC1KDM4EEGLN1 | |
| SCHEMBL6170787 | 0.70 | DYRK1A (0.42) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL7197087 | 0.70 | GRM2 (0.40) | RAB9AKLK7ALDH1A1CYP3A4NPC1 | |
| SCHEMBL7199062 | 0.70 | SMN1; SMN2 (0.49) | ALDH1A1NPC1HSD17B10EGLN1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | claimed |
| WO-2000003990-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | claimed |