Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825768 | 0.92 | MAOA (0.47) | MAOAPARP1TOP2ANUAK1PDGFRB | |
| SCHEMBL7826517 | 0.86 | MAOA (0.52) | MAOAPARP1DYRK1AHTR6KDM4E | |
| SCHEMBL7824605 | 0.85 | CTSV (0.43) | MAOADYRK1A | |
| SCHEMBL7827211 | 0.84 | HSD17B10 (0.51) | PARP1KDM4EALDH1A1 | |
| SCHEMBL7829082 | 0.84 | CTSV (0.44) | MAOADYRK1AALDH1A1SMN1; SMN2 | |
| SCHEMBL7816229 | 0.82 | MAOA (0.47) | MAOA | |
| SCHEMBL8068050 | 0.82 | XDH (0.48) | MAOAPARP1HRH3KDM4ESIGMAR1 | |
| SCHEMBL7827564 | 0.81 | MAOA (0.47) | MAOA | |
| SCHEMBL7826811 | 0.81 | ALDH1A1 (0.40) | MAOADYRK1AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7826292 | 0.81 | KDM4E (0.47) | MAOADYRK1AHTR6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |