Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862852 | 0.94 | PTPN1 (0.47) | PKMCA12CA1CA2CA9 | |
| SCHEMBL7869445 | 0.93 | PKM (0.43) | PKMCA12CA1CA2CA9 | |
| SCHEMBL7869400 | 0.92 | CA12 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9574752 | 0.90 | L3MBTL1 (0.53) | PKMMEN1KMT2AALDH1A1P4HTM | |
| SCHEMBL7862740 | 0.89 | ALDH1A1 (0.48) | PKMCA12CA1CA2CA9 | |
| SCHEMBL7869429 | 0.89 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1EGFRP4HTM | |
| SCHEMBL7862672 | 0.88 | L3MBTL1 (0.47) | PKMMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7869467 | 0.87 | MEN1 (0.48) | PKMCA12CA1CA2CA9 | |
| SCHEMBL9018504 | 0.87 | CA12 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL7862839 | 0.86 | SMN1; SMN2 (0.48) | PKMALDH1A1P4HTMKDM4EBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |