Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 9/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698653 | 0.87 | LMNA (0.47) | ALDH1A1MAPTITGB3ITGA2BF2R | |
| SCHEMBL4702813 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL4701810 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MEN1MAPTKMT2AITGB3 | |
| SCHEMBL4701020 | 0.79 | P2RY12 (0.43) | ITGB3ITGA2BGAA | |
| SCHEMBL7900498 | 0.79 | CCR1 (0.46) | ITGB3ITGA2BF2RGAA | |
| SCHEMBL4698338 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL7892913 | 0.78 | ITGB3 (0.40) | ALDH1A1ITGB3ITGA2BF2RGAA | |
| SCHEMBL7955769 | 0.78 | HPGD (0.47) | ITGB3ITGA2BGAAPOLBHPGD | |
| SCHEMBL7904100 | 0.78 | ITGB3 (0.41) | ITGB3ITGA2BF2RGAA | |
| SCHEMBL20530282 | 0.77 | POLB (0.46) | KMT2AITGB3ITGA2BGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | claimed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | claimed |
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |