Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789823 | 0.88 | ADAMTS4 (0.54) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL6798909 | 0.83 | ADAMTS4 (0.70) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL7897307 | 0.82 | ADAMTS4 (0.47) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL27465878 | 0.80 | ALDH1A1 (0.50) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL1186251 | 0.80 | MMP2 (0.50) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL8445730 | 0.80 | MMP2 (0.59) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL1185524 | 0.80 | MMP2 (0.50) | MMP13ADAMTS4MMP2MMP1ALDH1A1 | |
| SCHEMBL7669662 | 0.80 | MMP9 (0.62) | MMP2ALDH1A1HSD17B10L3MBTL1MMP9 | |
| SCHEMBL29540524 | 0.79 | HSD17B10 (0.54) | MMP13MMP2MMP1ALDH1A1HSD17B10 | |
| SCHEMBL6799581 | 0.76 | TSHR (0.51) | MMP13ADAMTS4MMP2MMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034071-A1 | Thioaryl sulfonamide hydroxamic acid compounds | PHARMACIA CORPORATION | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034071-A1 | Thioaryl sulfonamide hydroxamic acid compounds | MMP10, MMP1, MMP3 | MMP13 11/4885ADAMTS4 21/4885MMP2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.