Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913291 | 0.90 | ALOX5 (0.42) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7916991 | 0.83 | SLC6A3 (0.42) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7911681 | 0.81 | MAPT (0.36) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7902850 | 0.78 | PGR (0.33) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7930844 | 0.76 | PGR (0.33) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL7916616 | 0.73 | PDE4D (0.48) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7907060 | 0.73 | ALOX5 (0.42) | ALDH1A1MAPTLMNAL3MBTL1JAK2 | |
| SCHEMBL7913175 | 0.71 | MAOB (0.33) | ALDH1A1MAPTLMNAALOX12SMN1; SMN2 | |
| SCHEMBL7911301 | 0.71 | NLRP3 (0.35) | ALDH1A1LMNAKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7915330 | 0.69 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |