Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902850 | 0.80 | PGR (0.33) | RAB9AKMT2ASMN1; SMN2PGRLMNA | |
| SCHEMBL7913175 | 0.75 | MAOB (0.33) | SMN1; SMN2PGRLMNAALDH1A1 | |
| SCHEMBL7911681 | 0.75 | MAPT (0.36) | KMT2ASMN1; SMN2PGRLMNAALDH1A1 | |
| SCHEMBL7920535 | 0.72 | DHFR (0.33) | — | |
| SCHEMBL7913291 | 0.71 | ALOX5 (0.42) | KMT2AMAPK1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7915330 | 0.67 | MEN1 (0.36) | KMT2A | |
| SCHEMBL7921942 | 0.66 | CHRM3 (0.31) | KMT2ALMNAALDH1A1 | |
| SCHEMBL7916993 | 0.63 | ESR2 (0.35) | KMT2ADRD2DRD4DRD3PGR | |
| SCHEMBL3792406 | 0.63 | PDE4B (0.62) | RAB9AKMT2ATSHRL3MBTL1 | |
| SCHEMBL7931521 | 0.62 | ADORA3 (0.39) | NLRP3RAB9AGRM2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |