Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784072 | 0.88 | ABCB1 (0.60) | ABCB1ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL30758793 | 0.88 | ABCB1 (0.60) | ABCB1ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5628749 | 0.86 | ALDH1A1 (0.64) | ABCB1ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL11614404 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL2999532 | 0.79 | LMNA (0.77) | ABCB1ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL433401 | 0.79 | CCNB2 (0.72) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL29537861 | 0.79 | CCNB2 (0.72) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL27679877 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL1311076 | 0.78 | HDAC8 (0.65) | ABCB1ALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL2573994 | 0.78 | TUBB1 (0.57) | ABCB1ALDH1A1TDP1TUBB1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562030-B2 | Process for the synthesis of olopatadine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-02-07 | — | — | US | disclosed |
| US-20160280677-A1 | A PROCESS FOR THE SYNTHESIS OF OLOPATADINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-09-29 | — | — | US | disclosed |
| WO-2014147647-A1 | A PROCESS FOR THE SYNTHESIS OF OLOPATADINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-09-25 | — | — | WO | disclosed |
| US-6225352-B1 | USEFUL AS AGENTS IN THE TREATMENT OF CANCER, ALZHEIMERS DISEASE, THROMBOSIS, INFLAMMATORY DISEASES, AND BACTERIAL RESISTANCE | WARNER-LAMBERT COMPANY | 2001-05-01 | — | — | US | disclosed |
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280677-A1 | A PROCESS FOR THE SYNTHESIS OF OLOPATADINE | QDPR, OPRK1, PNMT | ABCB1 1689/4885ALDH1A1 1045/4885HPGD 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.